Vascular & Nitric Oxide

    PEMF and Nitric Oxide in Metabolic Syndrome: Mayo Clinic RCT

    Grade BRandomized controlled trial2019

    What did this study find?

    This randomized double-blind Mayo Clinic trial treated forty-four adults with metabolic syndrome using pulsed electromagnetic fields. Plasma nitric oxide rose against baseline, and blood pressure improvement was concentrated among participants who were hypertensive at entry. Benefit therefore appears to depend on starting physiology rather than applying evenly across patients.

    What are the details of this record?

    Full citation
    PEMF and Nitric Oxide in Metabolic Syndrome: Mayo Clinic RCT. Blood Press. 2019. PMID: 31394939.
    Journal
    Blood Press
    Study design
    Randomized controlled trial
    Sample size and population
    44 adults with metabolic syndrome
    Evidence grade
    Grade B on the BioReg grading scale
    Reported findings
    Randomized double-blind. Increased plasma nitric oxide vs baseline; BP improvement concentrated in hypertensive subjects.

    A positive PEMF study is not evidence for a specific device unless the signal parameters studied, frequency, intensity, waveform, and exposure duration, are reasonably comparable to what that device produces. Where this record does not list those parameters, the source report did not publish them. See the grading methodology. Library last reviewed 2026-08-27.