Chronic Pain

    Neurofeedback for Chronic Pain: Meta-Analysis

    Grade B+Systematic review and meta-analysis2020

    What did this study find?

    Twenty-one studies of EEG and fMRI neurofeedback for chronic pain were pooled in this 2020 analysis. Reported pain reduction ranged widely, from six to eighty-two percent, with ten studies clearing the thirty percent threshold considered clinically meaningful. The overall effect was medium. Wide variation across protocols makes individual outcomes hard to predict.

    What are the details of this record?

    Full citation
    Roy R, et al. Effects of neurofeedback in the management of chronic pain: A systematic review and meta-analysis. Eur J Pain. 2020;24(8):1440-1457.
    Journal
    European Journal of Pain
    Authors
    Roy R, et al.
    Study design
    Systematic review and meta-analysis
    Sample size and population
    Not reported in the published record
    Evidence grade
    Grade B+ on the BioReg grading scale
    Reported findings
    Meta-analysis of 21 studies on EEG/fMRI neurofeedback. Pain reduction ranged 6-82%, with 10 studies showing clinically significant (>30%) reduction. Overall medium effect size (Cohen's d -0.76).
    DOI
    No DOI recorded
    Related categories
    Chronic Pain (category grade A-)

    A positive PEMF study is not evidence for a specific device unless the signal parameters studied, frequency, intensity, waveform, and exposure duration, are reasonably comparable to what that device produces. Where this record does not list those parameters, the source report did not publish them. See the grading methodology. Library last reviewed 2026-08-27.